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Peptide record

TPDB26734

Antibacterial Anticancer Antifungal Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB26734
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 7-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WSRKWKW
Physicochemical Analysis
C54H73N15O9
ANDCEQGHILMFPTYV
W
1076.27
11.64
3
0
3
+3
-2.63
-2.257
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
16500
1533.07
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
1
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
7
C54H73N15O9
1076.27
11.64
+3
-2.63
-2.257
Evidence Records 3 records
Evidence 1 Activity

Activity

<2% Hemolysis
Toxicity
512 µg/mL
Hemolytic Cytotoxic
<2% Hemolysis | 512 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel non-cytotoxic antimicrobial peptides WSKK11 and WSRR11 with potent activity against Cutibacterium acnes. | J Antimicrob Chemother | 2022
Evidence 2 Activity

Activity

15% Cytotoxicity
Toxicity
512 µg/mL
Cytotoxic
15% Cytotoxicity | 512 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Novel non-cytotoxic antimicrobial peptides WSKK11 and WSRR11 with potent activity against Cutibacterium acnes. | J Antimicrob Chemother | 2022
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human dermal fibroblasts

Target

Human dermal fibroblasts

Source & Reference

NA
DBAASP
Novel non-cytotoxic antimicrobial peptides WSKK11 and WSRR11 with potent activity against Cutibacterium acnes. | J Antimicrob Chemother | 2022