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Peptide record

TPDB26733

Antibacterial Anticancer Antifungal Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB26733
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WSRKWKRKWKW
Physicochemical Analysis
C83H119N25O13
ANDCEQGHILMFPTYV
KW
1675.02
12.44
6
0
4
+6
-1.69
-2.636
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
22000
1313.42
1
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
4
K
0
M
0
F
0
P
1
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 1 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
11
C83H119N25O13
1675.02
12.44
+6
-1.69
-2.636
Evidence Records 3 records
Evidence 1 Activity

Activity

<2% Hemolysis
Toxicity
512 µg/mL
Hemolytic Cytotoxic
<2% Hemolysis | 512 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel non-cytotoxic antimicrobial peptides WSKK11 and WSRR11 with potent activity against Cutibacterium acnes. | J Antimicrob Chemother | 2022
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Novel non-cytotoxic antimicrobial peptides WSKK11 and WSRR11 with potent activity against Cutibacterium acnes. | J Antimicrob Chemother | 2022
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human dermal fibroblasts

Target

Human dermal fibroblasts

Source & Reference

NA
DBAASP
Novel non-cytotoxic antimicrobial peptides WSKK11 and WSRR11 with potent activity against Cutibacterium acnes. | J Antimicrob Chemother | 2022