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Peptide record

TPDB26698

Antibacterial Anticancer Toxicity standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB26698
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 6-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WRTWRT
Physicochemical Analysis
C42H60N14O9
ANDCEQGHILKMFPSYV
RTW
905.03
12.40
2
0
2
+2
-1.80
-2.033
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
11000
1215.43
2
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
2
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 2 W: 2 Y: 0 V: 0
Chemical Descriptors
6
C42H60N14O9
905.03
12.40
+2
-1.80
-2.033
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>256 µM
Hemolytic Cytotoxic
10% Hemolysis | >256 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The design of cell-selective tryptophan and arginine-rich antimicrobial peptides by introducing hydrophilic uncharged residues. | Acta Biomater | 2022
Evidence 2 Activity

Activity

10% Cell death
Toxicity
>256 µM
Cytotoxic
10% Cell death | >256 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
The design of cell-selective tryptophan and arginine-rich antimicrobial peptides by introducing hydrophilic uncharged residues. | Acta Biomater | 2022
Evidence 3 Activity

Activity

10% Cell death
Toxicity
>256 µM
Cytotoxic
10% Cell death | >256 | µM | target cell: Intestinal Porcine Epithelial Cells IPEC-J2

Target

Intestinal Porcine Epithelial Cells IPEC-J2

Source & Reference

NA
DBAASP
The design of cell-selective tryptophan and arginine-rich antimicrobial peptides by introducing hydrophilic uncharged residues. | Acta Biomater | 2022