Peptide record

TPDB26661

Antibacterial Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB26661
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WPLVIRTVIAGYNLYRAIKKK
Physicochemical Analysis
C120H196N32O26
DCEQHMFS
IK
2503.08
10.95
5
0
12
+5
-0.37
0.129
130.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
8480
338.78
4
Residue Composition
number
2
A
2
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
2
L
3
K
0
M
0
F
1
P
0
S
1
T
1
W
2
Y
2
V
Amino Acid Distribution
A: 2 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 2 K: 3 M: 0 F: 0 P: 1 S: 0 T: 1 W: 1 Y: 2 V: 2
Chemical Descriptors
21
C120H196N32O26
2503.08
10.95
+5
-0.37
0.129
Evidence Records 1 records
Evidence 1 Activity

Activity

60% Killing
Toxicity
30 µg/mL
Cytotoxic
60% Killing | 30 | µg/mL | target cell: Chicken macrophages HD-11

Target

Chicken macrophages HD-11

Source & Reference

NA
DBAASP
Avian antimicrobial peptides: in vitro and in ovo characterization and protection from early chick mortality caused by yolk sac infection. | Sci Rep | 2021