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Peptide record

TPDB26607

Antibacterial Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB26607
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 9-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WLRRWWIRV
Physicochemical Analysis
C68H99N21O10
ANDCEQGHKMFPSTY
RW
1370.67
12.70
3
0
6
+3
-3.92
-0.411
118.89
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
16500
1203.79
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 1
Chemical Descriptors
9
C68H99N21O10
1370.67
12.70
+3
-3.92
-0.411
Evidence Records 3 records
Evidence 1 Activity

Activity

1.87 ±0.12% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
1.87 ±0.12% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022
Evidence 2 Activity

Activity

4.13 ±0.28% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
4.13 ±0.28% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022
Evidence 3 Activity

Activity

19.6 ±0.5% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
19.6 ±0.5% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022