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Peptide record

TPDB26600

Antibacterial Antifungal Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB26600
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 15-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
WLNAKRHHGYKRKFH
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C92H136N32O18
DCEQIMPSTV
HK
1978.30
11.59
8
0
5
+5
3.62
-1.867
32.67
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
6990
3.53
2
Residue Composition
number
1
A
2
R
1
N
0
D
0
C
0
E
0
Q
1
G
3
H
0
I
1
L
3
K
0
M
1
F
0
P
0
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 3 I: 0 L: 1 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
15 reviewed residue count
C92H136N32O18 sequence-only estimate (linear, free termini)
1978.30 sequence-only estimate (linear, free termini)
11.59 sequence-only estimate (linear, free termini)
+5 sequence-only estimate (linear, free termini)
3.62 sequence-only estimate (linear, free termini)
-1.867 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Antifungal Activity and Action Mechanism of Histatin 5-Halocidin Hybrid Peptides against Candida ssp. | PLoS One | 2016