Peptide record

TPDB26595

Antibacterial Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB26595
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WLLWIALRKKR
Physicochemical Analysis
C73H119N21O12
NDCEQGHMFPSTYV
L
1482.88
12.42
4
0
7
+4
-2.26
-0.082
150.91
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
11000
741.80
0
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
2
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
11
C73H119N21O12
1482.88
12.42
+4
-2.26
-0.082
Evidence Records 3 records
Evidence 1 Activity

Activity

7.03% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
7.03% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022
Evidence 2 Activity

Activity

10.46% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
10.46% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022
Evidence 3 Activity

Activity

19.4% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
19.4% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022