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Peptide record

TPDB26590

Antibacterial Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB26590
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 9-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WLLLLWRRR
Physicochemical Analysis
C64H102N20O10
ANDCEQGHIKMFPSTYV
L
1311.64
12.70
3
0
6
+3
-3.51
-0.011
173.33
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
11000
838.64
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
0
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
9
C64H102N20O10
1311.64
12.70
+3
-3.51
-0.011
Evidence Records 3 records
Evidence 1 Activity

Activity

16.44 ±0.89% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
16.44 ±0.89% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022
Evidence 2 Activity

Activity

19.8 ±0.76% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
19.8 ±0.76% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022
Evidence 3 Activity

Activity

36.71 ±3.91% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
36.71 ±3.91% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022