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Peptide record

TPDB26589

Antibacterial Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB26589
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 9-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WLLLLLRRR
Physicochemical Analysis
C59H103N19O10
ANDCEQGHIKMFPSTYV
L
1238.59
12.70
3
0
6
+3
-2.22
0.511
216.67
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
444.05
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
5
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 5 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
9
C59H103N19O10
1238.59
12.70
+3
-2.22
0.511
Evidence Records 3 records
Evidence 1 Activity

Activity

11.89 ±1.24% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
11.89 ±1.24% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022
Evidence 2 Activity

Activity

20.52 ±1.25% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
20.52 ±1.25% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022
Evidence 3 Activity

Activity

36.35 ±3% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
36.35 ±3% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Matching amino acids membrane preference profile to improve activity of antimicrobial peptides. | Commun Biol | 2022