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Peptide record

TPDB26579

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB26579
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WIKKIWKKIIKEIK
Physicochemical Analysis
C93H156N22O17
ARNDCQGHLMFPSTYV
K
1854.40
10.82
6
1
7
+5
2.71
-0.443
139.29
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
11000
593.18
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
5
I
0
L
6
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 5 L: 0 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
14
C93H156N22O17
1854.40
10.82
+5
2.71
-0.443
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Design of Antimicrobial Peptides with Cell-Selective Activity and Membrane-Acting Mechanism against Drug-Resistant Bacteria | Antibiotics (Basel) | 2022
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Design of Antimicrobial Peptides with Cell-Selective Activity and Membrane-Acting Mechanism against Drug-Resistant Bacteria | Antibiotics (Basel) | 2022
Evidence 3 Activity

Activity

95% Cytotoxicity
Toxicity
200 µM
Cytotoxic
95% Cytotoxicity | 200 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Design of Antimicrobial Peptides with Cell-Selective Activity and Membrane-Acting Mechanism against Drug-Resistant Bacteria | Antibiotics (Basel) | 2022