Back to search

Peptide record

TPDB26538

Antibacterial Antifungal standard
32 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB26538
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 32-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
WKSESVCTPGCVTGILQTCFLQSITCNCRLSK
Physicochemical Analysis
C149H245N41O46S5
ADHMY
C
3507.13
8.14
3
1
9
+2
1.60
0.266
79.06
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5750
163.95
16
Residue Composition
number
0
A
1
R
1
N
0
D
5
C
1
E
2
Q
2
G
0
H
2
I
3
L
2
K
0
M
1
F
1
P
4
S
4
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 5 E: 1 Q: 2 G: 2 H: 0 I: 2 L: 3 K: 2 M: 0 F: 1 P: 1 S: 4 T: 4 W: 1 Y: 0 V: 2
Chemical Descriptors
32
C149H245N41O46S5
3507.13
8.14
+2
1.60
0.266
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against Gram-positive bacteria including B. amyloliquefaciens ATCC 15841, or L-S60, or L-H15 (diameter of inhibition zone: 16.0-16.2 mm), B. cereus ATCC 14579 (16.4 mm), L. lactis NZ9000 or MG1363 (9.1-9.4 mm), L. plantarum S-35 or gamma-35 (10.3-11 mm), S. aureus ATCC 29213, or 43300, or 26112 (16.1-16.4 mm), and E. faecalis ATCC 29212 (16.2 mm), or 51299 (8.2 mm), or M2 (6.3 mm) but not active against E.coli DH5alpha, or BL21, or BW25113, or JM109 (0 mm), and S.cerevisiae (0 mm), P.pastoris GS115 (0 mm). Also show great biophysical characteristics such as thermostability, pH-insensitive, resistance to chemical reagents, and sensitivity to various human proteases. Updated 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against Gram-positive bacteria including B. amyloliquefaciens ATCC 15841, or L-S60, or L-H15 (diameter of inhibition zone: 16.0-16.2 mm), B. cereus ATCC 14579 (16.4 mm), L. lactis NZ9000 or MG1363 (9.1-9.4 mm), L. plantarum S-35 or gamma-35 (10.3-11 mm), S. aureus ATCC 29213, or 43300, or 26112 (16.1-16.4 mm), and E. faecalis ATCC 29212 (16.2 mm), or 51299 (8.2 mm), or M2 (6.3 mm) but not active against E.coli DH5alpha, or BL21, or BW25113, or JM109 (0 mm), and S.cerevisiae (0 mm), P.pastoris GS115 (0 mm). Also show great biophysical characteristics such as thermostability, pH-insensitive, resistance to chemical reagents, and sensitivity to various human proteases. Updated 7/2021