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Peptide record

TPDB26496

Antibacterial Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB26496
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 7-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WFKIIKK
Physicochemical Analysis
C50H79N11O8
ARNDCEQGHLMPSTYV
K
962.25
10.84
3
0
4
+3
-0.63
-0.114
111.43
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
571.58
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
3
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
7
C50H79N11O8
962.25
10.84
+3
-0.63
-0.114
Evidence Records 3 records
Evidence 1 Activity

Activity

9.71% Cytotoxicity
Toxicity
1000 µg/mL
Cytotoxic
9.71% Cytotoxicity | 1000 | µg/mL | target cell: Human skin fibroblasts

Target

Human skin fibroblasts

Source & Reference

NA
DBAASP
AurH1: a new heptapeptide derived from Aurein1.2 antimicrobial peptide with specific and exclusive fungicidal activity. | J Pept Sci | 2019
Evidence 2 Activity

Activity

IC50
Toxicity
>1000 µg/mL
Cytotoxic
IC50 | >1000 | µg/mL | target cell: Human skin fibroblasts

Target

Human skin fibroblasts

Source & Reference

NA
DBAASP
AurH1: a new heptapeptide derived from Aurein1.2 antimicrobial peptide with specific and exclusive fungicidal activity. | J Pept Sci | 2019
Evidence 3 Activity

Activity

3.43% Hemolysis
Toxicity
1000 µg/mL
Hemolytic Cytotoxic
3.43% Hemolysis | 1000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
AurH1: a new heptapeptide derived from Aurein1.2 antimicrobial peptide with specific and exclusive fungicidal activity. | J Pept Sci | 2019