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Peptide record

TPDB26441

Antibacterial Anticancer Antiviral Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB26441
Antibacterial Anticancer Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Antiviral, and other sources) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
WEQKIEELLKKAEEQQKKNEEELKKLEKC
Physicochemical Analysis
C159H266N42O52S1
RDGHMFPSTYV
E
3630.17
5.15
8
9
7
-1
23.45
-1.848
70.69
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
151.51
5
Residue Composition
number
1
A
0
R
1
N
0
D
1
C
9
E
3
Q
0
G
0
H
1
I
4
L
8
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 1 E: 9 Q: 3 G: 0 H: 0 I: 1 L: 4 K: 8 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
29
C159H266N42O52S1
3630.17
5.15
-1
23.45
-1.848
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
40.27 µM
Cytotoxic
50% Cytotoxicity | 40.27 | µM | target cell: Human PBMC

Target

Human PBMC

Source & Reference

NA
DBAASP
Design and Characterization of Cholesterylated Peptide HIV-1/2 Fusion Inhibitors With Extremely Potent and Long-Lasting Antiviral Activity. | J Virol | 2019
Evidence 2 Activity

Activity

50% Cytotoxicity
Toxicity
25.31 µM
Cytotoxic
50% Cytotoxicity | 25.31 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Design and Characterization of Cholesterylated Peptide HIV-1/2 Fusion Inhibitors With Extremely Potent and Long-Lasting Antiviral Activity. | J Virol | 2019
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: PBMC: 50% Cytotoxicity=40.27 µM HEK293T cells: 50% Cytotoxicity=25.31 µM

Target

erythrocytes

Source & Reference

NA
DRAMP
J Virol. 2019 May 15 93(11):e02312-18.