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Peptide record

TPDB26419

Antibacterial Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB26419
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 25-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WAKKAAKIGAKLLPSVVKLFKGSGQ
Physicochemical Analysis
C124H209N33O29
RNDCEHMTY
K
2626.23
11.21
6
0
12
+6
1.75
0.084
101.60
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
209.43
3
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
1
Q
3
G
0
H
1
I
3
L
6
K
0
M
1
F
1
P
2
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 1 L: 3 K: 6 M: 0 F: 1 P: 1 S: 2 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
25
C124H209N33O29
2626.23
11.21
+6
1.75
0.084
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
5 µM
Hemolytic Cytotoxic
0% Hemolysis | 5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Uncoupling Amphipathicity and Hydrophobicity: Role of Charge Clustering in Membrane Interactions of Cationic Antimicrobial Peptides. | Biochemistry | 2021
Evidence 2 Activity

Activity

1% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
1% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Uncoupling Amphipathicity and Hydrophobicity: Role of Charge Clustering in Membrane Interactions of Cationic Antimicrobial Peptides. | Biochemistry | 2021