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Peptide record

TPDB26370

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB26370
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
VVVNVLVKVLPPPVV
Physicochemical Analysis
C77H135N17O17
ARDCEQGHIMFSTWY
V
1571.02
10.10
1
0
10
+1
2.20
1.933
206.67
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
1
K
0
M
0
F
3
P
0
S
0
T
0
W
0
Y
8
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 1 M: 0 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 8
Chemical Descriptors
15
C77H135N17O17
1571.02
10.10
+1
2.20
1.933
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

Staphylococcus aureus TISTR 517

Source & Reference

NA

Other

active against S. aureus TISTR 517 (MIC 2 ug/ml), MRSA isolate 142 (MIC 2 ug/ml), MRSA isolate 1096 (MIC 2 ug/ml), MRSA isolate 2468 (MIC
Evidence 2 Activity

Activity

3.40±0.29% Hemolysis
Toxicity
2 µg/mL
Hemolytic Cytotoxic
3.40±0.29% Hemolysis | 2 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Purification and Characterization of Novel Anti-MRSA Peptides Produced by Brevibacillus sp. SPR-20. | Molecules | 2022
Evidence 3 Activity

Activity

5.52±0.92% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
5.52±0.92% Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Purification and Characterization of Novel Anti-MRSA Peptides Produced by Brevibacillus sp. SPR-20. | Molecules | 2022
Evidence 4 Activity

Activity

62.23±0.69% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
62.23±0.69% Hemolysis | 64 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Purification and Characterization of Novel Anti-MRSA Peptides Produced by Brevibacillus sp. SPR-20. | Molecules | 2022