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Peptide record

TPDB26339

Antibacterial Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB26339
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 7-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
VWRRRWV
Physicochemical Analysis
C50H76N18O8
ANDCEQGHILKMFPSTY
R
1057.27
12.70
3
0
4
+3
-1.13
-0.986
82.86
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
11000
1040.42
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 2
Chemical Descriptors
7
C50H76N18O8
1057.27
12.70
+3
-1.13
-0.986
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>256 µM
Hemolytic Cytotoxic
10% Hemolysis | >256 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Short, mirror-symmetric antimicrobial peptides centered on "RRR" have broad-spectrum antibacterial activity with low drug resistance and toxicity. | Acta Biomater | 2022
Evidence 2 Activity

Activity

IC50
Toxicity
>128 µM
Cytotoxic
IC50 | >128 | µM | target cell: Chinese hamster ovary cells CHO-K1

Target

Chinese hamster ovary cells CHO-K1

Source & Reference

NA
DBAASP
Short, mirror-symmetric antimicrobial peptides centered on "RRR" have broad-spectrum antibacterial activity with low drug resistance and toxicity. | Acta Biomater | 2022