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Peptide record

TPDB26263

Antibacterial Antiparasitic Hemolysis Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB26263
Antibacterial Antiparasitic Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia dbAMP 3.0 i2APP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 8-aa standard natural multi-activity (Antibacterial, Antiparasitic, Hemolysis, and other sources) peptide sequence curated from Peptipedia, dbAMP 3.0, i2APP, and other sources, with an available 3D structural model.
Sequence
VRRRRRPR
Physicochemical Analysis
C46H90N26O9
ANDCEQGHILKMFSTWY
R
1151.39
13.10
6
0
1
+6
5.38
-3.050
36.25
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
8
C46H90N26O9
1151.39
13.10
+6
5.38
-3.050
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>100 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Leishmanicidal activity of synthetic antimicrobial peptides in an infection model with human dendritic cells. | Peptides | 2011
Evidence 2 Activity

Activity

50% Cell death
Toxicity
37.57±0.27 µg/mL
Cytotoxic
50% Cell death | 37.57±0.27 | µg/mL | target cell: Human dendritic cells

Target

Human dendritic cells

Source & Reference

NA
DBAASP
Leishmanicidal activity of synthetic antimicrobial peptides in an infection model with human dendritic cells. | Peptides | 2011
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis