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Peptide record

TPDB26262

Antibacterial Toxicity modified_plain modified
13 amino acids
Basic Information
3D PDB MODEL
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TPDB26262
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 13-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
VRRPXWWWXFLRR
Physicochemical Analysis
C82H116N26O12
ANDCEQGHIKMSTY
R
1657.99
12.88
4
0
6
+4
-3.48
-0.885
52.31
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
16500
995.18
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
1
F
1
P
0
S
0
T
3
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 1 S: 0 T: 0 W: 3 Y: 0 V: 1
Chemical Descriptors
13
C82H116N26O12
1657.99
12.88
+4
-3.48
-0.885
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
<5% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidin-derived Trp/Pro-rich antimicrobial peptides with lysine peptoid residue (Nlys): therapeutic index and plausible mode of action | J Pept Sci | 2007