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Peptide record

TPDB26247

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB26247
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
VQRWLIVWRIRKG
Physicochemical Analysis
C81H132N26O15
ANDCEHMFPSTY
R
1710.10
12.71
4
0
7
+4
-0.73
-0.146
134.62
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
11000
643.24
1
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
2
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 2 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 2
Chemical Descriptors
13
C81H132N26O15
1710.10
12.71
+4
-0.73
-0.146
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Toxicity
147.9 µg/mL
Cytotoxic
IC50 | 147.9 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens. | Nat Commun | 2023