Peptide record

TPDB26246

Antibacterial Antifungal Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB26246
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia ToxinPred 3.0
standard
No
A 8-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and ToxinPred 3.0, with an available 3D structural model.
Sequence
VRLLRRRI
Physicochemical Analysis
C47H92N20O9
ANDCEQGHKMFPSTWY
R
1081.38
12.88
4
0
4
+4
1.88
-0.213
182.50
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
2
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
8
C47H92N20O9
1081.38
12.88
+4
1.88
-0.213
Evidence Records 6 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
34.56 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 34.56 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of N-terminal modifications on the stability of antimicrobial peptide SAMP-A4 analogues against protease degradation. | J Pept Sci | 2021
Evidence 2 Activity

Activity

5% Hemolysis
Toxicity
69.26 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 69.26 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of N-terminal modifications on the stability of antimicrobial peptide SAMP-A4 analogues against protease degradation. | J Pept Sci | 2021
Evidence 3 Activity

Activity

5% Hemolysis
Toxicity
73.84 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 73.84 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of N-terminal modifications on the stability of antimicrobial peptide SAMP-A4 analogues against protease degradation. | J Pept Sci | 2021
Evidence 4 Activity

Activity

5% Hemolysis
Toxicity
84.98 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 84.98 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of N-terminal modifications on the stability of antimicrobial peptide SAMP-A4 analogues against protease degradation. | J Pept Sci | 2021
Evidence 5 Activity

Activity

5% Hemolysis
Toxicity
19.95 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 19.95 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of N-terminal modifications on the stability of antimicrobial peptide SAMP-A4 analogues against protease degradation. | J Pept Sci | 2021
Evidence 6 Activity

Activity

5% Hemolysis
Toxicity
22.16 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 22.16 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of N-terminal modifications on the stability of antimicrobial peptide SAMP-A4 analogues against protease degradation. | J Pept Sci | 2021