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Peptide record

TPDB26244

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB26244
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
VRLIVAVRIWRRG
Physicochemical Analysis
C73H128N26O14
NDCEQHKMFPSTY
R
1593.99
12.88
4
0
8
+4
0.26
0.608
164.62
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
5500
345.05
0
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
13
C73H128N26O14
1593.99
12.88
+4
0.26
0.608
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Toxicity
126.4 µg/mL
Cytotoxic
IC50 | 126.4 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens. | Nat Commun | 2023