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Peptide record

TPDB26222

Antibacterial standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB26222
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 14-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
VPLSRTVRCTCISI
Physicochemical Analysis
C65H118N20O19S2
ANDEQGHKMFWY
RCISTV
1547.89
9.19
2
0
5
+2
1.09
0.900
125.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
125
8.08
6
Residue Composition
number
0
A
2
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
2
I
1
L
0
K
0
M
0
F
1
P
2
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 0 M: 0 F: 0 P: 1 S: 2 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
14
C65H118N20O19S2
1547.89
9.19
+2
1.09
0.900
Evidence Records 1 records
Evidence 1 Activity

Activity

EC50
Antibacterial
18.1 µM

Target

B. anthracis Sterne 7702 bacilli

Source & Reference

NA

Other

P1 kills B. anthracis Sterne 7702 bacilli (EC50 18.1 uM), B. anthracis bacilli lacking the FtsX component of the FtsE/X complex (EC50 53.1 uM), B.