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Peptide record

TPDB26215

Antibacterial Antifungal Toxicity modified_plain modified
15 amino acids
Basic Information
3D PDB MODEL
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TPDB26215
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 15-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
VNXKKIXPKXIKVXK
Physicochemical Analysis
C61H115N17O13
ARDCEQGHLMFSTWY
K
1294.69
11.12
5
0
4
+5
5.34
-0.480
90.67
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
5
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 5 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
15
C61H115N17O13
1294.69
11.12
+5
5.34
-0.480
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>100 (82) µM
Hemolytic Cytotoxic
50% Hemolysis | >100 (82) | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effect of hydrocarbon stapling on the properties of ?-helical antimicrobial peptides isolated from the venom of hymenoptera. | Amino Acids | 2012