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Peptide record

TPDB26139

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB26139
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
VKLIVAVKIWKK
Physicochemical Analysis
C71H125N17O13
RNDCEQGHMFPSTY
K
1424.88
11.00
4
0
8
+4
0.97
0.892
178.33
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
5500
386.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
4
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
12
C71H125N17O13
1424.88
11.00
+4
0.97
0.892
Evidence Records 1 records
Evidence 1 Activity

Activity

7% Cytotoxicity
Toxicity
40 µM
Cytotoxic
7% Cytotoxicity | 40 | µM | target cell: Human PBMC

Target

Human PBMC

Source & Reference

NA
DBAASP
Influence of Non-natural Cationic Amino Acids on the Biological Activity Profile of Innate Defense Regulator Peptides. | J Med Chem | 2019