Back to search

Peptide record

TPDB26117

Antibacterial standard
23 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB26117
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 23-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
VGQFLGKIIKKVGNFVKGFSKVF
Physicochemical Analysis
C124H198N30O27
ARDCEHMPTWY
K
2541.12
11.12
5
0
11
+5
0.70
0.517
101.30
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
1
Q
4
G
0
H
2
I
1
L
5
K
0
M
4
F
0
P
1
S
0
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 4 H: 0 I: 2 L: 1 K: 5 M: 0 F: 4 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 4
Chemical Descriptors
23
C124H198N30O27
2541.12
11.12
+5
0.70
0.517
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.5-5.8 µg/mL

Target

Staphylococcus aureus 930918-3 or 30371 MRSA or 28841 MRSA

Source & Reference

NA

Other

active against Gram+ S. aureus 930918-3 or 30371 MRSA or 28841 MRSA (MIC 2.5-5.8 ug/ml), E. faecalis CDC 21 (MIC 2.6 ug/ml), E. faecium 94-132 (MIC 0.3-0.5 ug/ml), L. monocytoge
Evidence 2 Activity

Activity

MIC
Antibacterial
2.6 µg/mL

Target

Enterococcus faecalis CDC 21

Source & Reference

NA

Other

active against Gram+ S. aureus 930918-3 or 30371 MRSA or 28841 MRSA (MIC 2.5-5.8 ug/ml), E. faecalis CDC 21 (MIC 2.6 ug/ml), E. faecium 94-132 (MIC 0.3-0.5 ug/ml), L. monocytogenes EGD (MIC 0.4 ug/ml), Gram- E. co
Evidence 3 Activity

Activity

MIC
Antibacterial
0.3-0.5 µg/mL

Target

E. faecium 94-132

Source & Reference

NA

Other

18-3 or 30371 MRSA or 28841 MRSA (MIC 2.5-5.8 ug/ml), E. faecalis CDC 21 (MIC 2.6 ug/ml), E. faecium 94-132 (MIC 0.3-0.5 ug/ml), L. monocytogenes EGD (MIC 0.4 ug/ml), Gram- E. coli ML-35p or mcr 106 or BAS 849 (MIC 0.
Evidence 4 Activity

Activity

MIC
Antibacterial
0.4 µg/mL

Target

L. monocytogenes EGD

Source & Reference

NA

Other

.5-5.8 ug/ml), E. faecalis CDC 21 (MIC 2.6 ug/ml), E. faecium 94-132 (MIC 0.3-0.5 ug/ml), L. monocytogenes EGD (MIC 0.4 ug/ml), Gram- E. coli ML-35p or mcr 106 or BAS 849 (MIC 0.4-2.3 ug/ml), S. typhimurium 14028S or
Evidence 5 Activity

Activity

MIC
Antibacterial
0.4-2.3 µg/mL

Target

Escherichia coli ML-35p or mcr 106 or BAS 849

Source & Reference

NA

Other

g/ml), E. faecium 94-132 (MIC 0.3-0.5 ug/ml), L. monocytogenes EGD (MIC 0.4 ug/ml), Gram- E. coli ML-35p or mcr 106 or BAS 849 (MIC 0.4-2.3 ug/ml), S. typhimurium 14028S or 7953S (MIC 1.3-1.5 ug/ml), K. pneumoniae 2270 (MIC 2.8 ug/ml),
Evidence 6 Activity

Activity

MIC
Antibacterial
1.3-1.5 µg/mL

Target

S. typhimurium 14028S or 7953S

Source & Reference

NA

Other

enes EGD (MIC 0.4 ug/ml), Gram- E. coli ML-35p or mcr 106 or BAS 849 (MIC 0.4-2.3 ug/ml), S. typhimurium 14028S or 7953S (MIC 1.3-1.5 ug/ml), K. pneumoniae 2270 (MIC 2.8 ug/ml), P. aeruginosa SBI-N or MR2123 or MR3007 (MIC 0.7-0.9
Evidence 7 Activity

Activity

MIC
Antibacterial
2.8 µg/mL

Target

Klebsiella pneumoniae 2270

Source & Reference

NA

Other

r 106 or BAS 849 (MIC 0.4-2.3 ug/ml), S. typhimurium 14028S or 7953S (MIC 1.3-1.5 ug/ml), K. pneumoniae 2270 (MIC 2.8 ug/ml), P. aeruginosa SBI-N or MR2123 or MR3007 (MIC 0.7-0.9 ug/ml).
Evidence 8 Activity

Activity

MIC
Antibacterial
0.7-0.9 µg/mL

Target

Pseudomonas aeruginosa SBI-N or MR2123 or MR3007

Source & Reference

NA

Other

, S. typhimurium 14028S or 7953S (MIC 1.3-1.5 ug/ml), K. pneumoniae 2270 (MIC 2.8 ug/ml), P. aeruginosa SBI-N or MR2123 or MR3007 (MIC 0.7-0.9 ug/ml).