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Peptide record

TPDB26112

Antibacterial Antiparasitic Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB26112
Antibacterial Antiparasitic Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia dbAMP 3.0 HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antiparasitic, Hemolysis, and other sources) peptide sequence curated from Peptipedia, dbAMP 3.0, HemoPI, and other sources, with an available 3D structural model.
Sequence
VFIDILDKMENAIHKAAQAGIG
Physicochemical Analysis
C105H172N28O31S1
RCPSTWY
AI
2354.75
5.28
3
3
12
-1
4.67
0.391
120.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
4
A
0
R
1
N
2
D
0
C
1
E
1
Q
2
G
1
H
4
I
1
L
2
K
1
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 2 C: 0 E: 1 Q: 1 G: 2 H: 1 I: 4 L: 1 K: 2 M: 1 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
22
C105H172N28O31S1
2354.75
5.28
-1
4.67
0.391
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>100 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Leishmanicidal activity of synthetic antimicrobial peptides in an infection model with human dendritic cells. | Peptides | 2011
Evidence 2 Activity

Activity

50% Cell death
Toxicity
>100 µg/mL
Cytotoxic
50% Cell death | >100 | µg/mL | target cell: Human dendritic cells

Target

Human dendritic cells

Source & Reference

NA
DBAASP
Leishmanicidal activity of synthetic antimicrobial peptides in an infection model with human dendritic cells. | Peptides | 2011
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis