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Peptide record

TPDB26101

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB26101
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
VFRLKKWIQAVI
Physicochemical Analysis
C74H121N19O14
NDCEGHMPSTY
IKV
1500.89
11.64
3
0
8
+3
-0.82
0.758
154.17
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
5500
366.45
1
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
2
I
1
L
2
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 2 L: 1 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
12
C74H121N19O14
1500.89
11.64
+3
-0.82
0.758
Evidence Records 1 records
Evidence 1 Activity

Activity

20.7% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
20.7% Hemolysis | 200 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Thrombin-Derived Peptides Potentiate the Activity of Gram-Positive-Specific Antibiotics against Gram-Negative Bacteria. | Molecules | 2021