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Peptide record

TPDB26100

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB26100
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
VFRLKKWIAKVI
Physicochemical Analysis
C75H125N19O13
NDCEQGHMPSTY
K
1500.94
11.73
4
0
8
+4
-0.41
0.725
154.17
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
5500
366.44
0
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
3
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
12
C75H125N19O13
1500.94
11.73
+4
-0.41
0.725
Evidence Records 1 records
Evidence 1 Activity

Activity

3.5% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
3.5% Hemolysis | 200 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Thrombin-Derived Peptides Potentiate the Activity of Gram-Positive-Specific Antibiotics against Gram-Negative Bacteria. | Molecules | 2021