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Peptide record

TPDB26083

Antibacterial Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB26083
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 29-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
VDQTVFKDIWWRMKQWKQRVKKRAAKYNV
Physicochemical Analysis
C173H271N51O40S1
CEGHLPS
K
3737.43
11.17
9
2
13
+7
4.91
-1.138
60.34
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
17990
481.35
6
Residue Composition
number
2
A
3
R
1
N
2
D
0
C
0
E
3
Q
0
G
0
H
1
I
0
L
6
K
1
M
1
F
0
P
0
S
1
T
3
W
1
Y
4
V
Amino Acid Distribution
A: 2 R: 3 N: 1 D: 2 C: 0 E: 0 Q: 3 G: 0 H: 0 I: 1 L: 0 K: 6 M: 1 F: 1 P: 0 S: 0 T: 1 W: 3 Y: 1 V: 4
Chemical Descriptors
29
C173H271N51O40S1
3737.43
11.17
+7
4.91
-1.138
Evidence Records 1 records
Evidence 1 Activity

Activity

<7% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
<7% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
LcCCL28-25, Derived from Piscine Chemokine, Exhibits Antimicrobial Activity against Gram-Negative and Gram-Positive Bacteria In Vitro and In Vivo | Microbiol Spectr | 2022