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Peptide record

TPDB26059

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB26059
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
VDKPPYLPRPRPPRRIYNRC
Physicochemical Analysis
C112H181N37O26S1
AEQGHMFSTW
P
2493.96
11.23
6
1
5
+5
6.47
-1.530
53.50
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
2980
119.49
4
Residue Composition
number
0
A
5
R
1
N
1
D
1
C
0
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
0
F
6
P
0
S
0
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 5 N: 1 D: 1 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 6 S: 0 T: 0 W: 0 Y: 2 V: 1
Chemical Descriptors
20
C112H181N37O26S1
2493.96
11.23
+5
6.47
-1.530
Evidence Records 1 records
Evidence 1 Activity

Activity

15% Cytotoxicity
Toxicity
100 µM
Cytotoxic
15% Cytotoxicity | 100 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Development of Antimicrobial Peptide-Antibiotic Conjugates to Improve the Outer Membrane Permeability of Antibiotics Against Gram-Negative Bacteria. | ACS Infect Dis | 2022