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Peptide record

TPDB26057

Antibacterial Antiviral Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB26057
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia and AI4AVP, with an available 3D structural model.
Sequence
VCSCRLVFCRR
Physicochemical Analysis
C55H96N20O13S3
ANDEQGHIKMPTWY
RC
1341.67
9.30
3
0
4
+3
0.29
0.745
88.18
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
125
9.32
4
Residue Composition
number
0
A
3
R
0
N
0
D
3
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 3 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
11
C55H96N20O13S3
1341.67
9.30
+3
0.29
0.745
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
42 µM
Cytotoxic
50% Cytotoxicity | 42 | µM | target cell: Human retinal epithelial cells ARPE-19

Target

Human retinal epithelial cells ARPE-19

Source & Reference

NA
DBAASP
The Human ?-Defensin-Derived Peptide HD5(1-9) Inhibits Cellular Attachment and Entry of Human Cytomegalovirus | Antiviral Res | 2020