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Peptide record

TPDB26053

Antibacterial Antifungal Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB26053
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia Antifungipept
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
VDCSGACSPFEVPPCGSRDCRCIPIGLVVGFCIYPTG
Physicochemical Analysis
C165H257N43O49S6
NQHKMW
C
3819.47
4.31
2
3
12
-1
2.91
0.611
76.22
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1865
48.83
11
Residue Composition
number
1
A
2
R
0
N
2
D
6
C
1
E
0
Q
5
G
0
H
3
I
1
L
0
K
0
M
2
F
5
P
3
S
1
T
0
W
1
Y
4
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 2 C: 6 E: 1 Q: 0 G: 5 H: 0 I: 3 L: 1 K: 0 M: 0 F: 2 P: 5 S: 3 T: 1 W: 0 Y: 1 V: 4
Chemical Descriptors
37
C165H257N43O49S6
3819.47
4.31
-1
2.91
0.611
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

aM1 showed a cytotoxic effect against insect Sf9 cells. The 0.1% DMSO, a negative control, did not show significant cytotoxic effect, while 10% Triton-X 100, a positive control, destroyed over 99% cell death after 24 h treatment.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

aM1 showed a cytotoxic effect against insect Sf9 cells. The 0.1% DMSO, a negative control, did not show significant cytotoxic effect, while 10% Triton-X 100, a positive control, destroyed over 99% cell death after 24 h treatment.
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Chinese hamster ovary cells CHO-K1

Target

Chinese hamster ovary cells CHO-K1

Source & Reference

NA
DBAASP
Astratides: Insulin-Modulating, Insecticidal, and Antifungal Cysteine-Rich Peptides from Astragalus membranaceus. | J Nat Prod | 2019