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Peptide record

TPDB26003

Antibacterial Antiparasitic Hemolysis Toxicity standard
51 amino acids
Basic Information
3D PDB MODEL
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TPDB26003
Antibacterial Antiparasitic Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia dbAMP 3.0 HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 51-aa standard natural multi-activity (Antibacterial, Antiparasitic, Hemolysis, and other sources) peptide sequence curated from Peptipedia, dbAMP 3.0, HemoPI, and other sources, with an available 3D structural model.
Sequence
TVLQTVVHKVGKTQFGCPAYQGYCDDHCQDIEKKEGFCHGFKCKCGIPMGF
Physicochemical Analysis
C250H379N67O71S7
RNSW
G
5683.59
7.65
9
5
15
+1
11.12
-0.308
47.65
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
3355
59.03
15
Residue Composition
number
1
A
0
R
0
N
3
D
6
C
2
E
4
Q
7
G
3
H
2
I
1
L
6
K
1
M
4
F
2
P
0
S
3
T
0
W
2
Y
4
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 3 C: 6 E: 2 Q: 4 G: 7 H: 3 I: 2 L: 1 K: 6 M: 1 F: 4 P: 2 S: 0 T: 3 W: 0 Y: 2 V: 4
Chemical Descriptors
51
C250H379N67O71S7
5683.59
7.65
+1
11.12
-0.308
Evidence Records 3 records
Evidence 1 Activity

Activity

7% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
7% Hemolysis | 10 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
MeuTXKbeta1, a scorpion venom-derived two-domain potassium channel toxin-like peptide with cytolytic activity | Biochim Biophys Acta | 2010
Evidence 2 Activity

Activity

17% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
17% Hemolysis | 20 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
MeuTXKbeta1, a scorpion venom-derived two-domain potassium channel toxin-like peptide with cytolytic activity | Biochim Biophys Acta | 2010
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis