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Peptide record

TPDB26001

Antibacterial Antifungal standard
55 amino acids
Basic Information
3D PDB MODEL
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TPDB26001
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 55-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
TVKCGMNGKMPCKHGAFYTDTCDKNVFYRCVWGRPVKKHCGRGLVWNPRGFCDYA
Physicochemical Analysis
C278H420N82O71S8
EQIS
G
6303.38
9.45
12
3
18
+7
5.53
-0.520
37.09
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
15845
251.37
15
Residue Composition
number
2
A
4
R
3
N
3
D
6
C
0
E
0
Q
7
G
2
H
0
I
1
L
6
K
2
M
3
F
3
P
0
S
3
T
2
W
3
Y
5
V
Amino Acid Distribution
A: 2 R: 4 N: 3 D: 3 C: 6 E: 0 Q: 0 G: 7 H: 2 I: 0 L: 1 K: 6 M: 2 F: 3 P: 3 S: 0 T: 3 W: 2 Y: 3 V: 5
Chemical Descriptors
55
C278H420N82O71S8
6303.38
9.45
+7
5.53
-0.520
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.2-25 µM

Target

M. albican

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
t B. subtilis, S. aureus, S. luteus and B. megaterium (MIC < 5uM), fungi C. albicans and M. albican (MIC 6.2-25 uM). Only weakly active against V. Parahaemolyticus and P. aeruginosa (MIC 50-100 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
50-100 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP

Other

bicans and M. albican (MIC 6.2-25 uM). Only weakly active against V. Parahaemolyticus and P. aeruginosa (MIC 50-100 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
6.2-25 µM

Target

M. albican

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
t B. subtilis, S. aureus, S. luteus and B. megaterium (MIC < 5uM), fungi C. albicans and M. albican (MIC 6.2-25 uM). Only weakly active against V. Parahaemolyticus and P. aeruginosa (MIC 50-100 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
50-100 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP CAFPdb Antifungipept

Other

bicans and M. albican (MIC 6.2-25 uM). Only weakly active against V. Parahaemolyticus and P. aeruginosa (MIC 50-100 uM).