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Peptide record

TPDB26000

Antibacterial Antifungal standard
55 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB26000
Antibacterial Antifungal
Anti-infective peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 55-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
TVKCGMNGKMPCKHGAFYTDTCDKNVFYRCVWGRPVKKACGRGLVWNPRGFCDYA
Physicochemical Analysis
C275H418N80O71S8
EQIS
G
6237.32
9.45
11
3
19
+7
4.40
-0.429
38.91
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
15845
254.04
15
Residue Composition
number
3
A
4
R
3
N
3
D
6
C
0
E
0
Q
7
G
1
H
0
I
1
L
6
K
2
M
3
F
3
P
0
S
3
T
2
W
3
Y
5
V
Amino Acid Distribution
A: 3 R: 4 N: 3 D: 3 C: 6 E: 0 Q: 0 G: 7 H: 1 I: 0 L: 1 K: 6 M: 2 F: 3 P: 3 S: 0 T: 3 W: 2 Y: 3 V: 5
Chemical Descriptors
55
C275H418N80O71S8
6237.32
9.45
+7
4.40
-0.429
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
25-50 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram-negative bacteria E. coli (MIC 25-50 uM), V. harveyi (MIC 25-50 uM), V-parahaemolyticus (MIC>50 uM), P-aeruginosa (MIC > 50 uM), G
Evidence 2 Activity

Activity

MIC
Antibacterial
25-50 µM

Target

V. harveyi

Source & Reference

dbAMP

Other

Active against Gram-negative bacteria E. coli (MIC 25-50 uM), V. harveyi (MIC 25-50 uM), V-parahaemolyticus (MIC>50 uM), P-aeruginosa (MIC > 50 uM), Gram-positive B. subtilis (M
Evidence 3 Activity

Activity

MIC
Antibacterial
1.2-1.5 µM

Target

B. subtilis

Source & Reference

dbAMP

Other

(MIC 25-50 uM), V-parahaemolyticus (MIC>50 uM), P-aeruginosa (MIC > 50 uM), Gram-positive B. subtilis (MIC 1.2-1.5 uM), S. aureus (MIC 2.5-5.0 uM), S. luteus (MIC 1.2-1.5 uM), B. megaterium (2.5-5 uM), and fu
Evidence 4 Activity

Activity

MIC
Antibacterial
2.5-5.0 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

icus (MIC>50 uM), P-aeruginosa (MIC > 50 uM), Gram-positive B. subtilis (MIC 1.2-1.5 uM), S. aureus (MIC 2.5-5.0 uM), S. luteus (MIC 1.2-1.5 uM), B. megaterium (2.5-5 uM), and fungi C. albicans (MIC 6.7-12.
Evidence 5 Activity

Activity

MIC
Antibacterial
1.2-1.5 µM

Target

S. luteus

Source & Reference

dbAMP

Other

sa (MIC > 50 uM), Gram-positive B. subtilis (MIC 1.2-1.5 uM), S. aureus (MIC 2.5-5.0 uM), S. luteus (MIC 1.2-1.5 uM), B. megaterium (2.5-5 uM), and fungi C. albicans (MIC 6.7-12.5 uM).
Evidence 6 Activity

Activity

MIC
Antibacterial
6.7-12.5 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

aureus (MIC 2.5-5.0 uM), S. luteus (MIC 1.2-1.5 uM), B. megaterium (2.5-5 uM), and fungi C. albicans (MIC 6.7-12.5 uM).
Evidence 7 Activity

Activity

MIC
Antifungal
25-50 µM

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram-negative bacteria E. coli (MIC 25-50 uM), V. harveyi (MIC 25-50 uM), V-parahaemolyticus (MIC>50 uM), P-aeruginosa (MIC > 50 uM), G
Evidence 8 Activity

Activity

MIC
Antifungal
25-50 µM

Target

V. harveyi

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram-negative bacteria E. coli (MIC 25-50 uM), V. harveyi (MIC 25-50 uM), V-parahaemolyticus (MIC>50 uM), P-aeruginosa (MIC > 50 uM), Gram-positive B. subtilis (M
Evidence 9 Activity

Activity

MIC
Antifungal
1.2-1.5 µM

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 25-50 uM), V-parahaemolyticus (MIC>50 uM), P-aeruginosa (MIC > 50 uM), Gram-positive B. subtilis (MIC 1.2-1.5 uM), S. aureus (MIC 2.5-5.0 uM), S. luteus (MIC 1.2-1.5 uM), B. megaterium (2.5-5 uM), and fu
Evidence 10 Activity

Activity

MIC
Antifungal
2.5-5.0 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

icus (MIC>50 uM), P-aeruginosa (MIC > 50 uM), Gram-positive B. subtilis (MIC 1.2-1.5 uM), S. aureus (MIC 2.5-5.0 uM), S. luteus (MIC 1.2-1.5 uM), B. megaterium (2.5-5 uM), and fungi C. albicans (MIC 6.7-12.
Evidence 11 Activity

Activity

MIC
Antifungal
1.2-1.5 µM

Target

S. luteus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

sa (MIC > 50 uM), Gram-positive B. subtilis (MIC 1.2-1.5 uM), S. aureus (MIC 2.5-5.0 uM), S. luteus (MIC 1.2-1.5 uM), B. megaterium (2.5-5 uM), and fungi C. albicans (MIC 6.7-12.5 uM).
Evidence 12 Activity

Activity

MIC
Antifungal
6.7-12.5 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

aureus (MIC 2.5-5.0 uM), S. luteus (MIC 1.2-1.5 uM), B. megaterium (2.5-5 uM), and fungi C. albicans (MIC 6.7-12.5 uM).