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Peptide record

TPDB25998

Antibacterial standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB25998
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 33-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
TTLRLNTLAYKVAWLVNVKAFWAAGRALKKVGR
Physicochemical Analysis
C174H284N50O40
DCEQHIMPS
A
3716.48
12.16
7
0
19
+7
-1.64
0.221
112.42
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
12490
336.07
6
Residue Composition
number
6
A
3
R
2
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
5
L
4
K
0
M
1
F
0
P
0
S
3
T
2
W
1
Y
4
V
Amino Acid Distribution
A: 6 R: 3 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 5 K: 4 M: 0 F: 1 P: 0 S: 0 T: 3 W: 2 Y: 1 V: 4
Chemical Descriptors
33
C174H284N50O40
3716.48
12.16
+7
-1.64
0.221
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

active against S. aureus ATCC 25923 (MIC 8 ug/ml), E. coli ATTCC 25922 (MIC 4 ug/ml), resistant S. aureus ATCC43300 (resistant to methicill
Evidence 2 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Escherichia coli ATTCC 25922

Source & Reference

NA

Other

active against S. aureus ATCC 25923 (MIC 8 ug/ml), E. coli ATTCC 25922 (MIC 4 ug/ml), resistant S. aureus ATCC43300 (resistant to methicillin MRSA and oxacillin), VRSA S. aur
Evidence 3 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

ug/ml), resistant S. aureus ATCC43300 (resistant to methicillin MRSA and oxacillin), VRSA S. aureus (MIC 16 ug/ml), and E. coli ATTCC35218 (MIC 8 ug/ml).
Evidence 4 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Escherichia coli ATTCC35218

Source & Reference

NA

Other

CC43300 (resistant to methicillin MRSA and oxacillin), VRSA S. aureus (MIC 16 ug/ml), and E. coli ATTCC35218 (MIC 8 ug/ml).