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Peptide record

TPDB25917

Antibacterial Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB25917
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 30-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
TKCFQWQRNMRKVRGPPVSCIKRDSPIQCI
Physicochemical Analysis
C154H256N50O40S4
AEHLY
R
3576.28
10.79
7
1
8
+6
6.64
-0.717
58.33
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
5625
157.29
10
Residue Composition
number
0
A
4
R
1
N
1
D
3
C
0
E
3
Q
1
G
0
H
3
I
0
L
3
K
1
M
1
F
3
P
2
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 4 N: 1 D: 1 C: 3 E: 0 Q: 3 G: 1 H: 0 I: 3 L: 0 K: 3 M: 1 F: 1 P: 3 S: 2 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
30
C154H256N50O40S4
3576.28
10.79
+6
6.64
-0.717
Evidence Records 1 records
Evidence 1 Activity

Activity

LC50
Toxicity
25.49±0.27 µg/mL
Cytotoxic
LC50 | 25.49±0.27 | µg/mL | target cell: Human PBMC

Target

Human PBMC

Source & Reference

NA
DBAASP
De novo expression and antibacterial potential of four lactoferricin peptides in cell-free protein synthesis system. | Biotechnol Rep (Amst) | 2020