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Peptide record

TPDB25878

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB25878
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
TALKSLSILKKLAKLNM
Physicochemical Analysis
C85H158N22O22S1
RDCEQGHFPWYV
L
1872.38
11.00
4
0
9
+4
1.10
0.447
149.41
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
5
L
4
K
1
M
0
F
0
P
2
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 5 K: 4 M: 1 F: 0 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C85H158N22O22S1
1872.38
11.00
+4
1.10
0.447
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
64-128 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

Active against E. coli ATCC 25922 (MIC 64-128 ug/ml), S.enteritidis (MIC 128 ug/ml), and S.aureus ATCC 29213 (MIC 128 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

S.enteritidis

Source & Reference

NA

Other

Active against E. coli ATCC 25922 (MIC 64-128 ug/ml), S.enteritidis (MIC 128 ug/ml), and S.aureus ATCC 29213 (MIC 128 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

S.aureus ATCC 29213

Source & Reference

NA

Other

Active against E. coli ATCC 25922 (MIC 64-128 ug/ml), S.enteritidis (MIC 128 ug/ml), and S.aureus ATCC 29213 (MIC 128 ug/ml).
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >128 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP