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Peptide record

TPDB25843

Antibacterial Toxicity standard
50 amino acids
Basic Information
3D PDB MODEL
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TPDB25843
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 50-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
SYQRIRSDHDSHSCANNRGWCRPTCFSHEYTDWFNNDVCGSYRCCRPGRR
Physicochemical Analysis
C249H365N87O77S6
LKM
R
6001.53
8.31
11
5
10
+3
9.92
-1.316
15.60
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
15845
264.02
22
Residue Composition
number
1
A
8
R
4
N
4
D
6
C
1
E
1
Q
3
G
3
H
1
I
0
L
0
K
0
M
2
F
2
P
6
S
2
T
2
W
3
Y
1
V
Amino Acid Distribution
A: 1 R: 8 N: 4 D: 4 C: 6 E: 1 Q: 1 G: 3 H: 3 I: 1 L: 0 K: 0 M: 0 F: 2 P: 2 S: 6 T: 2 W: 2 Y: 3 V: 1
Chemical Descriptors
50
C249H365N87O77S6
6001.53
8.31
+3
9.92
-1.316
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human bronchial epithelial cells

Target

Human bronchial epithelial cells

Source & Reference

NA
DBAASP
The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets | MBio | 2019
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Murine macrophage cells J774A.1

Target

Murine macrophage cells J774A.1

Source & Reference

NA
DBAASP
The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets | MBio | 2019