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Peptide record

TPDB25838

Antibacterial Antiparasitic Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB25838
Antibacterial Antiparasitic Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia dbAMP 3.0 HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Antiparasitic, Hemolysis, and other sources) peptide sequence curated from Peptipedia, dbAMP 3.0, HemoPI, and other sources, with an available 3D structural model.
Sequence
SWLSKTAKKLENSAKKRISEGIAIAQGPR
Physicochemical Analysis
C139H239N43O41
DCHMFYV
K
3168.69
11.08
7
2
10
+5
8.16
-0.738
81.03
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
5500
173.57
7
Residue Composition
number
4
A
2
R
1
N
0
D
0
C
2
E
1
Q
2
G
0
H
3
I
2
L
5
K
0
M
0
F
1
P
4
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 2 N: 1 D: 0 C: 0 E: 2 Q: 1 G: 2 H: 0 I: 3 L: 2 K: 5 M: 0 F: 0 P: 1 S: 4 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
29
C139H239N43O41
3168.69
11.08
+5
8.16
-0.738
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>100 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Leishmanicidal activity of synthetic antimicrobial peptides in an infection model with human dendritic cells. | Peptides | 2011
Evidence 2 Activity

Activity

50% Cell death
Toxicity
22.97±1.63 µg/mL
Cytotoxic
50% Cell death | 22.97±1.63 | µg/mL | target cell: Human dendritic cells

Target

Human dendritic cells

Source & Reference

NA
DBAASP
Leishmanicidal activity of synthetic antimicrobial peptides in an infection model with human dendritic cells. | Peptides | 2011
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis