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Peptide record

TPDB25817

Antibacterial Anticancer Antiviral Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB25817
Antibacterial Anticancer Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0 HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antiviral, and other sources) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
SWLRDIWDWICEVLSDFK
Physicochemical Analysis
C109H155N25O29S1
ANQGHMPTY
DW
2311.64
3.97
2
4
9
-2
-0.82
-0.033
102.78
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
16500
713.78
3
Residue Composition
number
0
A
1
R
0
N
3
D
1
C
1
E
0
Q
0
G
0
H
2
I
2
L
1
K
0
M
1
F
0
P
2
S
0
T
3
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 3 C: 1 E: 1 Q: 0 G: 0 H: 0 I: 2 L: 2 K: 1 M: 0 F: 1 P: 0 S: 2 T: 0 W: 3 Y: 0 V: 1
Chemical Descriptors
18
C109H155N25O29S1
2311.64
3.97
-2
-0.82
-0.033
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
3.46 µM
Hemolytic Cytotoxic
0% Hemolysis | 3.46 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational design of peptides with anti-HCV/HIV activities and enhanced specificity. | Chem Biol Drug Des | 2011
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis