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Peptide record

TPDB25783

Antibacterial Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB25783
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
SVIFGCTKSIPPICFVGFK
Physicochemical Analysis
C97H151N21O23S2
ARNDEQHLMWY
IF
2043.51
9.11
2
0
8
+2
-1.36
1.116
92.11
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
6.12
5
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
0
Q
2
G
0
H
3
I
0
L
2
K
0
M
3
F
2
P
2
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 0 K: 2 M: 0 F: 3 P: 2 S: 2 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
19
C97H151N21O23S2
2043.51
9.11
+2
-1.36
1.116
Evidence Records 3 records
Evidence 1 Activity

Activity

15% Killing
Toxicity
160 µg/mL
Cytotoxic
15% Killing | 160 | µg/mL | target cell: Human retinal epithelial cells ARPE-19

Target

Human retinal epithelial cells ARPE-19

Source & Reference

NA
DBAASP
Rational design of hyperstable antibacterial peptides for food preservation. | NPJ Sci Food | 2021
Evidence 2 Activity

Activity

25% Killing
Toxicity
200 µg/mL
Cytotoxic
25% Killing | 200 | µg/mL | target cell: Human retinal epithelial cells ARPE-19

Target

Human retinal epithelial cells ARPE-19

Source & Reference

NA
DBAASP
Rational design of hyperstable antibacterial peptides for food preservation. | NPJ Sci Food | 2021
Evidence 3 Activity

Activity

<5% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational design of hyperstable antibacterial peptides for food preservation. | NPJ Sci Food | 2021