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Peptide record

TPDB25766

Antibacterial Antifungal standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB25766
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
SSAPCTIYASVSASISATASWGC
Physicochemical Analysis
C94H146N24O34S2
RNDEQHLKMF
S
2220.45
5.18
0
0
10
-0
-3.02
0.696
68.26
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
7115
320.43
12
Residue Composition
number
5
A
0
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
2
I
0
L
0
K
0
M
0
F
1
P
7
S
2
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 0 K: 0 M: 0 F: 0 P: 1 S: 7 T: 2 W: 1 Y: 1 V: 1
Chemical Descriptors
23
C94H146N24O34S2
2220.45
5.18
-0
-3.02
0.696
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.11 µM

Target

Staphylococcus simulans 22

Source & Reference

NA

Other

Active against S. simulans 22 (MIC 0.11 uM), S. aureus SG511 or SG511 DapR or clinical isolate MRSA MB5393 (MIC 0.22-13.6 uM), M. tub
Evidence 2 Activity

Activity

MIC
Antibacterial
0.22-13.6 µM

Target

Staphylococcus aureus SG511 or SG511 DapR or clinical isolate MRSA MB5393

Source & Reference

NA

Other

Active against S. simulans 22 (MIC 0.11 uM), S. aureus SG511 or SG511 DapR or clinical isolate MRSA MB5393 (MIC 0.22-13.6 uM), M. tuberculosis H37Ra (MIC 13.6 uM), B. subtilis 168 (MIC 3.4 uM), clinical isolates C.
Evidence 3 Activity

Activity

MIC
Antibacterial
13.6 µM

Target

M. tuberculosis H37Ra

Source & Reference

NA

Other

11 uM), S. aureus SG511 or SG511 DapR or clinical isolate MRSA MB5393 (MIC 0.22-13.6 uM), M. tuberculosis H37Ra (MIC 13.6 uM), B. subtilis 168 (MIC 3.4 uM), clinical isolates C. difficile RyC 11872343 toxigenic (MIC
Evidence 4 Activity

Activity

MIC
Antibacterial
3.4 µM

Target

B. subtilis 168

Source & Reference

NA

Other

or clinical isolate MRSA MB5393 (MIC 0.22-13.6 uM), M. tuberculosis H37Ra (MIC 13.6 uM), B. subtilis 168 (MIC 3.4 uM), clinical isolates C. difficile RyC 11872343 toxigenic (MIC 3.4 uM), C. difficile RyC 119
Evidence 5 Activity

Activity

MIC
Antibacterial
3.4 µM

Target

Clostridioides difficile RyC 11872343 toxigenic

Source & Reference

NA

Other

uM), M. tuberculosis H37Ra (MIC 13.6 uM), B. subtilis 168 (MIC 3.4 uM), clinical isolates C. difficile RyC 11872343 toxigenic (MIC 3.4 uM), C. difficile RyC 11945271 toxigenic (1.7 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
0.11 µM

Target

Staphylococcus simulans 22

Source & Reference

Antifungipept

Other

Active against S. simulans 22 (MIC 0.11 uM), S. aureus SG511 or SG511 DapR or clinical isolate MRSA MB5393 (MIC 0.22-13.6 uM), M. tub
Evidence 7 Activity

Activity

MIC
Antifungal
0.22-13.6 µM

Target

Staphylococcus aureus SG511 or SG511 DapR or clinical isolate MRSA MB5393

Source & Reference

Antifungipept

Other

Active against S. simulans 22 (MIC 0.11 uM), S. aureus SG511 or SG511 DapR or clinical isolate MRSA MB5393 (MIC 0.22-13.6 uM), M. tuberculosis H37Ra (MIC 13.6 uM), B. subtilis 168 (MIC 3.4 uM), clinical isolates C.
Evidence 8 Activity

Activity

MIC
Antifungal
13.6 µM

Target

M. tuberculosis H37Ra

Source & Reference

Antifungipept

Other

11 uM), S. aureus SG511 or SG511 DapR or clinical isolate MRSA MB5393 (MIC 0.22-13.6 uM), M. tuberculosis H37Ra (MIC 13.6 uM), B. subtilis 168 (MIC 3.4 uM), clinical isolates C. difficile RyC 11872343 toxigenic (MIC
Evidence 9 Activity

Activity

MIC
Antifungal
3.4 µM

Target

B. subtilis 168

Source & Reference

Antifungipept

Other

or clinical isolate MRSA MB5393 (MIC 0.22-13.6 uM), M. tuberculosis H37Ra (MIC 13.6 uM), B. subtilis 168 (MIC 3.4 uM), clinical isolates C. difficile RyC 11872343 toxigenic (MIC 3.4 uM), C. difficile RyC 119
Evidence 10 Activity

Activity

MIC
Antifungal
3.4 µM

Target

Clostridioides difficile RyC 11872343 toxigenic

Source & Reference

Antifungipept

Other

uM), M. tuberculosis H37Ra (MIC 13.6 uM), B. subtilis 168 (MIC 3.4 uM), clinical isolates C. difficile RyC 11872343 toxigenic (MIC 3.4 uM), C. difficile RyC 11945271 toxigenic (1.7 uM).