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Peptide record

TPDB25752

Antibacterial Antifungal standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB25752
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept CAFPdb DRAMP dbAMP
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
SRSELIVHQRLF
Physicochemical Analysis
C66H109N21O18
ANDCGKMPTWY
RLS
1484.72
10.89
3
1
5
+1
2.95
-0.142
121.67
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
1
E
1
Q
0
G
1
H
1
I
2
L
0
K
0
M
1
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 1 I: 1 L: 2 K: 0 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
12
C66H109N21O18
1484.72
10.89
+1
2.95
-0.142
Evidence Records 14 records
Evidence 1 Activity

Activity

MIC
Antibacterial
10 µg/mL

Target

Candida albicans 01U or 38 U

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
DRAMP antibacterial activity supported by MIC records against bacterial target organisms. dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against C. albicans 01U or 38 U (MIC 10 ug/ml), C. parapsilosis (MIC 32 ug/ml), C. neoformans L26 (MIC 64 ug/ml), C. neoformans L30 (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

C. parapsilosis

Source & Reference

dbAMP DRAMP

Other

Active against C. albicans 01U or 38 U (MIC 10 ug/ml), C. parapsilosis (MIC 32 ug/ml), C. neoformans L26 (MIC 64 ug/ml), C. neoformans L30 (MIC 64 ug/ml), T.mentagrophytes (MI
Evidence 3 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

C. neoformans L26

Source & Reference

dbAMP DRAMP

Other

Active against C. albicans 01U or 38 U (MIC 10 ug/ml), C. parapsilosis (MIC 32 ug/ml), C. neoformans L26 (MIC 64 ug/ml), C. neoformans L30 (MIC 64 ug/ml), T.mentagrophytes (MIC 128 ug/ml), and T. rubrum (MIC 1
Evidence 4 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

C. neoformans L30

Source & Reference

dbAMP DRAMP

Other

or 38 U (MIC 10 ug/ml), C. parapsilosis (MIC 32 ug/ml), C. neoformans L26 (MIC 64 ug/ml), C. neoformans L30 (MIC 64 ug/ml), T.mentagrophytes (MIC 128 ug/ml), and T. rubrum (MIC 10 ug/ml). Parasites: inhibits T. c
Evidence 5 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

T.mentagrophytes

Source & Reference

dbAMP DRAMP

Other

losis (MIC 32 ug/ml), C. neoformans L26 (MIC 64 ug/ml), C. neoformans L30 (MIC 64 ug/ml), T.mentagrophytes (MIC 128 ug/ml), and T. rubrum (MIC 10 ug/ml). Parasites: inhibits T. cruzi (EC50 16.9 uM). MOA:parasite:
Evidence 6 Activity

Activity

MIC
Antibacterial
10 µg/mL

Target

T. rubrum

Source & Reference

dbAMP DRAMP

Other

6 (MIC 64 ug/ml), C. neoformans L30 (MIC 64 ug/ml), T.mentagrophytes (MIC 128 ug/ml), and T. rubrum (MIC 10 ug/ml). Parasites: inhibits T. cruzi (EC50 16.9 uM). MOA:parasite:T. cruzi: membrane active ( Me
Evidence 7 Activity

Activity

EC50
Antibacterial
16.9 µM

Target

T. cruzi

Source & Reference

dbAMP DRAMP

Other

/ml), T.mentagrophytes (MIC 128 ug/ml), and T. rubrum (MIC 10 ug/ml). Parasites: inhibits T. cruzi (EC50 16.9 uM). MOA:parasite:T. cruzi: membrane active ( Mengarda et al., 2026 ).
Evidence 8 Activity

Activity

MIC
Antifungal
10 µg/mL

Target

Candida albicans 01U or 38 U

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
DRAMP antifungal activity supported by activity records against fungal target organisms. dbAMP classified under the Anti-fungal function class.
Active against C. albicans 01U or 38 U (MIC 10 ug/ml), C. parapsilosis (MIC 32 ug/ml), C. neoformans L26 (MIC 64 ug/ml), C. neoformans L30 (MIC
Evidence 9 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

C. parapsilosis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against C. albicans 01U or 38 U (MIC 10 ug/ml), C. parapsilosis (MIC 32 ug/ml), C. neoformans L26 (MIC 64 ug/ml), C. neoformans L30 (MIC 64 ug/ml), T.mentagrophytes (MI
Evidence 10 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

C. neoformans L26

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against C. albicans 01U or 38 U (MIC 10 ug/ml), C. parapsilosis (MIC 32 ug/ml), C. neoformans L26 (MIC 64 ug/ml), C. neoformans L30 (MIC 64 ug/ml), T.mentagrophytes (MIC 128 ug/ml), and T. rubrum (MIC 1
Evidence 11 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

C. neoformans L30

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

or 38 U (MIC 10 ug/ml), C. parapsilosis (MIC 32 ug/ml), C. neoformans L26 (MIC 64 ug/ml), C. neoformans L30 (MIC 64 ug/ml), T.mentagrophytes (MIC 128 ug/ml), and T. rubrum (MIC 10 ug/ml). Parasites: inhibits T. c
Evidence 12 Activity

Activity

MIC
Antifungal
128 µg/mL

Target

T.mentagrophytes

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

losis (MIC 32 ug/ml), C. neoformans L26 (MIC 64 ug/ml), C. neoformans L30 (MIC 64 ug/ml), T.mentagrophytes (MIC 128 ug/ml), and T. rubrum (MIC 10 ug/ml). Parasites: inhibits T. cruzi (EC50 16.9 uM). MOA:parasite:
Evidence 13 Activity

Activity

MIC
Antifungal
10 µg/mL

Target

T. rubrum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

6 (MIC 64 ug/ml), C. neoformans L30 (MIC 64 ug/ml), T.mentagrophytes (MIC 128 ug/ml), and T. rubrum (MIC 10 ug/ml). Parasites: inhibits T. cruzi (EC50 16.9 uM). MOA:parasite:T. cruzi: membrane active ( Me
Evidence 14 Activity

Activity

EC50
Antifungal
16.9 µM

Target

T. cruzi

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

/ml), T.mentagrophytes (MIC 128 ug/ml), and T. rubrum (MIC 10 ug/ml). Parasites: inhibits T. cruzi (EC50 16.9 uM). MOA:parasite:T. cruzi: membrane active ( Mengarda et al., 2026 ).