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Peptide record

TPDB25748

Antibacterial Antifungal Hemolysis Toxicity standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB25748
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP PD_Hemolysis
standard
No
A 3-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from Peptipedia, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Sequence
SRR
Physicochemical Analysis
C15H31N9O5
ANDCEQGHILKMFPTWYV
R
417.47
12.40
2
0
0
+2
1.75
-3.267
0.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
3
C15H31N9O5
417.47
12.40
+2
1.75
-3.267
Evidence Records 6 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
41.54 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 41.54 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ultrashort Cationic Lipopeptides-Effect of N-Terminal Amino Acid and Fatty Acid Type on Antimicrobial Activity and Hemolysis | Molecules | 2020
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
75.46±0.73 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 75.46±0.73 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Glycosylated Lipopeptides-Synthesis and Evaluation of Antimicrobial Activity and Cytotoxicity | Biomolecules | 2023
Evidence 3 Activity

Activity

IC50
Toxicity
4.02±1.17 µg/mL
Cytotoxic
IC50 | 4.02±1.17 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Glycosylated Lipopeptides-Synthesis and Evaluation of Antimicrobial Activity and Cytotoxicity | Biomolecules | 2023
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
82.31±1.36 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 82.31±1.36 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Glycosylated Lipopeptides-Synthesis and Evaluation of Antimicrobial Activity and Cytotoxicity | Biomolecules | 2023
Evidence 5 Activity

Activity

IC50
Toxicity
8.28±1.18 µg/mL
Cytotoxic
IC50 | 8.28±1.18 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Glycosylated Lipopeptides-Synthesis and Evaluation of Antimicrobial Activity and Cytotoxicity | Biomolecules | 2023
Evidence 6 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis