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Peptide record

TPDB25730

Antibacterial Anticancer Antifungal standard
41 amino acids
Basic Information
3D PDB MODEL
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TPDB25730
Antibacterial Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
Peptipedia CancerPPD 2.0 dbACP Antifungipept
standard
No
A 41-aa standard-residue multi-activity (Antibacterial, Anticancer, and Antifungal) peptide sequence curated from Peptipedia, CancerPPD 2.0, dbACP, and other sources, with an available 3D structural model.
Sequence
SPRVRRRYGRPFGGRPFVGGQFGGRPGCVCIRSPCPCANYG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C192H299N67O48S4
DEHLKMTW
G
4442.15
11.59
8
0
10
+8
2.37
-0.563
33.17
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
3230
0.73
10
Residue Composition
number
1
A
8
R
1
N
0
D
4
C
0
E
1
Q
9
G
0
H
1
I
0
L
0
K
0
M
3
F
6
P
2
S
0
T
0
W
2
Y
3
V
Amino Acid Distribution
A: 1 R: 8 N: 1 D: 0 C: 4 E: 0 Q: 1 G: 9 H: 0 I: 1 L: 0 K: 0 M: 0 F: 3 P: 6 S: 2 T: 0 W: 0 Y: 2 V: 3
Chemical Descriptors
41 reviewed residue count
C192H299N67O48S4 sequence-only estimate (linear, free termini)
4442.15 sequence-only estimate (linear, free termini)
11.59 sequence-only estimate (linear, free termini)
+8 sequence-only estimate (linear, free termini)
2.37 sequence-only estimate (linear, free termini)
-0.563 sequence-only estimate (linear, free termini)
Evidence Records 6 records
Evidence 1 Activity

Activity

IC50
Antibacterial
20 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Recombinant rSs-arasin showed antimicrobial activity against S. aureus (IC50 20 uM), P. aeruginosa (IC50 40 uM), and E. coli (IC50 20 uM). It also inhibited human cervical c
Evidence 2 Activity

Activity

IC50
Antibacterial
40 µM

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

Recombinant rSs-arasin showed antimicrobial activity against S. aureus (IC50 20 uM), P. aeruginosa (IC50 40 uM), and E. coli (IC50 20 uM). It also inhibited human cervical carcinoma (HeLa, IC50 3.06 uM
Evidence 3 Activity

Activity

IC50
Antibacterial
20 µM

Target

Escherichia coli

Source & Reference

NA

Other

ed antimicrobial activity against S. aureus (IC50 20 uM), P. aeruginosa (IC50 40 uM), and E. coli (IC50 20 uM). It also inhibited human cervical carcinoma (HeLa, IC50 3.06 uM) and colon carcinoma (HT-
Evidence 4 Activity

Activity

IC50
Antifungal
20 µM

Target

Staphylococcus aureus

Source & Reference

Antifungipept

Other

Recombinant rSs-arasin showed antimicrobial activity against S. aureus (IC50 20 uM), P. aeruginosa (IC50 40 uM), and E. coli (IC50 20 uM). It also inhibited human cervical c
Evidence 5 Activity

Activity

IC50
Antifungal
40 µM

Target

Pseudomonas aeruginosa

Source & Reference

Antifungipept

Other

Recombinant rSs-arasin showed antimicrobial activity against S. aureus (IC50 20 uM), P. aeruginosa (IC50 40 uM), and E. coli (IC50 20 uM). It also inhibited human cervical carcinoma (HeLa, IC50 3.06 uM
Evidence 6 Activity

Activity

IC50
Antifungal
20 µM

Target

Escherichia coli

Source & Reference

Antifungipept

Other

ed antimicrobial activity against S. aureus (IC50 20 uM), P. aeruginosa (IC50 40 uM), and E. coli (IC50 20 uM). It also inhibited human cervical carcinoma (HeLa, IC50 3.06 uM) and colon carcinoma (HT-