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Peptide record

TPDB25676

Antibacterial Anticancer Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB25676
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
SLLSLIRKLIW
Physicochemical Analysis
C65H112N16O14
ANDCEQGHMFPTYV
L
1341.70
11.49
2
0
7
+2
-2.65
1.209
212.73
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
5500
409.93
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
4
L
1
K
0
M
0
F
0
P
2
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 4 K: 1 M: 0 F: 0 P: 0 S: 2 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
11
C65H112N16O14
1341.70
11.49
+2
-2.65
1.209
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
1.56 µM
Hemolytic Cytotoxic
0% Hemolysis | 1.56 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Natural and redesigned wasp venom peptides with selective antitumoral activity. | Beilstein J Org Chem | 2018
Evidence 2 Activity

Activity

MHC
Toxicity
1.56 µm
Hemolytic Cytotoxic
Hemolytic_activity: Human red blood cells: MHC=1.56 µmol/L | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Beilstein J Org Chem. 2018 Jul 6 14:1693-1703.