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Peptide record

TPDB25675

Antibacterial standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB25675
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 23-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
SLPKEEQIGKSSTRGRKSSRRKK
Physicochemical Analysis
C109H199N41O35
ANDCHMFWYV
KS
2644.03
12.01
9
2
2
+7
13.20
-2.035
33.91
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
7
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
2
E
1
Q
2
G
0
H
1
I
1
L
5
K
0
M
0
F
1
P
5
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 2 Q: 1 G: 2 H: 0 I: 1 L: 1 K: 5 M: 0 F: 0 P: 1 S: 5 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
23
C109H199N41O35
2644.03
12.01
+7
13.20
-2.035
Evidence Records 1 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

LD90 (lethal dose killing > 90%): active against E. coli WBB01 or ATCC 11775 (LD90 0.39-6.25 ug/ml), S.enterica sv Minnesota strain R595 or R60 or PXG1 (L90 12.5-25 ug/ml), P.mirabilis R45 (LD90 >100 ug/ml), B.cepacia WaaC::kann (LD90 >100 ug/ml), and P. aeruginosa ATCC 1014 (LD90 0.1 ug/ml). Warning: other bacteria not tested.