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Peptide record

TPDB25661

Antibacterial Antifungal Toxicity standard
121 amino acids
Basic Information
3D PDB MODEL
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TPDB25661
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia Antifungipept
standard
No
A 121-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTGCNPKKDRYSYSWKDKTIVCGENNSCLKELCECDKAVAICLRENLNTYNKKYRYYLKPLCKKADAC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C596H953N167O175S15
K
13739.04
8.87
25
12
38
+11
1.95
-0.664
60.50
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
21275
1.55
43
Residue Composition
number
7
A
5
R
8
N
6
D
14
C
6
E
1
Q
9
G
1
H
3
I
11
L
19
K
1
M
1
F
4
P
5
S
5
T
1
W
10
Y
4
V
Amino Acid Distribution
A: 7 R: 5 N: 8 D: 6 C: 14 E: 6 Q: 1 G: 9 H: 1 I: 3 L: 11 K: 19 M: 1 F: 1 P: 4 S: 5 T: 5 W: 1 Y: 10 V: 4
Chemical Descriptors
121 reviewed residue count
C596H953N167O175S15 sequence-only estimate (linear, free termini)
13739.04 sequence-only estimate (linear, free termini)
8.87 sequence-only estimate (linear, free termini)
+11 sequence-only estimate (linear, free termini)
1.95 sequence-only estimate (linear, free termini)
-0.664 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against S. aureus, V. cholerae and E. coli. No MIC found.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against S. aureus, V. cholerae and E. coli. No MIC found.