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Peptide record

TPDB25654

Antibacterial Anticancer Antiviral Toxicity standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB25654
Antibacterial Anticancer Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia AI4AVP DRAMP DRAVP 2.0
standard
No
A 36-aa standard natural multi-activity (Antibacterial, Anticancer, Antiviral, and other sources) peptide sequence curated from Peptipedia, AI4AVP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKEL
Physicochemical Analysis
C196H317N43O64S1
RCGHPW
EL
4331.98
4.14
5
10
16
-5
15.99
-0.433
119.17
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
2980
68.79
7
Residue Composition
number
1
A
0
R
1
N
3
D
0
C
7
E
1
Q
0
G
0
H
3
I
7
L
5
K
1
M
1
F
0
P
2
S
1
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 3 C: 0 E: 7 Q: 1 G: 0 H: 0 I: 3 L: 7 K: 5 M: 1 F: 1 P: 0 S: 2 T: 1 W: 0 Y: 2 V: 1
Chemical Descriptors
36
C196H317N43O64S1
4331.98
4.14
-5
15.99
-0.433
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. | Sci Adv | 2019
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: HEK293T/ACE2 cells

Target

HEK293T/ACE2 cells

Source & Reference

NA
DBAASP
A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. | Sci Adv | 2019
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. | Sci Adv | 2019